Objectives: To evaluate the effect of tamsulosin on reducing the serum levels of prostate-specific antigen (PSA) in patients with lower urinary tract symptoms and an elevated PSA level. Methods: From June 2004 to July 2006, patients with lower urinary tract symptoms, a PSA level of >or=4 ng/mL, and a maximal flow rate of
The most accurate predictor of prostate cancer on biopsy was percent free PSA (0.68) versus age (0.50), total PSA (0.57), or rectal examination findings (0.58). Of patients with percent free PSA below 14%, 59% had prostate cancer.
The combination of total Prostate-Specific Antigen (PSA) level and the ratio of free PSA were set as criteria for evaluating the risk of PCa. Multivariable logistic regression was used in race-stratified analyses to compute odds ratios (OR) and 95% confidence intervals (95% CI) comparing high PCa risk with low PCa risk.
According to a 2015 review in the journal Medicine, testosterone replacement therapy also doesn't increase prostate specific antigen (PSA) levels. PSA is a protein that's elevated in the
Semen / chemistry. Prostate-Specific Antigen. To determine the effects of ejaculation on serum PSA, we measured serum levels just before masturbation and 24 hours and 5 days later in a study group (n=25) aged between 23 and 25 years. In the study group, 16 cases showed a decrease (mean 22.37%, range 10-50%) in serum PSA levels 24 hours after ej
PSA levels are affected by acute and chronic prostatitis, as well as by physical trauma and inflammation Only about 25% of men with tPSA in the 4-10 ng/mL range have a subsequent positive biopsy. 1,4 Determining PSA testing accuracy has been difficult because men with typical tPSA values will not undergo biopsy unless their DRE is abnormal.
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psa and free psa levels